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Coenzyme Q10

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Catalog No. T2796Cas No. 303-98-0
Alias Ubiquinone-10, CoQ10

Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.

Coenzyme Q10

Coenzyme Q10

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Purity: 99.88%
Catalog No. T2796Alias Ubiquinone-10, CoQ10Cas No. 303-98-0
Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
200 mg$42In StockIn Stock
500 mg$91-In Stock
1 g$136-In Stock
5 g$197-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.88%
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Product Introduction

Bioactivity
Description
Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.
In vivo
Coenzyme Q10 plays a critical role in the electron transport chain and participates in cellular aerobic respiration, generating energy in the form of adenosine triphosphate (ATP). It effectively protects retinal cells from damage under conditions of oxidative stress or hypoglycemia. Moreover, in vitro, Coenzyme Q10 safeguards cells against cytotoxicity induced by glutamate in its various obstructive forms.
SynonymsUbiquinone-10, CoQ10
Chemical Properties
Molecular Weight863.34
FormulaC59H90O4
Cas No.303-98-0
SmilesC(/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)\C)\C)\C)\C)\C)\C)\C)C=1C(=O)C(OC)=C(OC)C(=O)C1C
Relative Density.0.9145 g/cm3 (Estimated)
Storage & Solubility Information
Storagestore at low temperature,The compound is unstable in solution. Please use soon | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMF: 1 mg/mL (1.16 mM), Sonication and heating are recommended.
DMSO: < 1 mg/mL (insoluble or slightly soluble), The compound is unstable in solution, please use soon.
Solution Preparation Table
DMF
1mg5mg10mg50mg
1 mM1.1583 mL5.7915 mL11.5829 mL57.9146 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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